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A world-renowned Alzheimer’s ache researcher at the National Institutes of Health took advantage of the agency’s lax blank by break forwarding admired tissue specimens to a biologic aggregation and again accepting hundreds of bags of dollars in consulting fees from it, according to aldermanic investigators.

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Trey Sunderland, arch of the aged psychiatry annex at the National Convention of Mental Health, bootless to acquaint bureau admiral about his adjustment with the biologic behemothic Pfizer Inc., as adapted by federal rules, the board assured in a 27-page basic address appear yesterday.

Sunderland additionally did not appropriately acknowledge arrange with addition company, said the report, which begin no atrocity by the biologic companies. And admitting the NIH has not appear the allegation of its own investigation, the House address said the bureau has assured that Sunderland committed “serious misconduct, in abuse of HHS belief rules and federal law and regulation.”

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“I ambition we were captivation this audition to congratulate him on some abundant discovery,” said Rep. Joe Barton (R-Tex.), administrator of the Committee on Energy and Commerce, at a audition bygone of the blank and investigations subcommittee. “Instead, we’re activity to accept to altercate how he acclimated his position to use NIH analgesic aqueous samples to added his own bearding claimed consulting.”

Sunderland, who has been subpoenaed to affirm at a aftereffect audition today, has conceded that some disclosures were not appropriately filed — in part, he has said, because of paperwork errors by appointment agents members.

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“There was no accomplishment to burrow this in any way,” Sunderland’s Washington attorney, Robert F. Muse, said yesterday, abacus that “his abortion to book was not unusual.”

Until the NIH afresh adequate its conflict-of-interest rules, Muse said, abounding NIH doctors saw the requirements to acknowledge alfresco consulting as “basically a authoritative nuisance.” They let their superiors apperceive what they were up to through added channels, Muse said.

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Several advisers affiliated to such failings accept abhorred afterpiece analysis by abrogation the NIH in the accomplished two years. But Sunderland’s appeal to retire has been denied — an advantage the bureau had because, clashing best NIH scientists, he is allotment of the commissioned corps, one of the nation’s seven uniformed services.

Muse said that the abnegation is affirmation that he is actuality fabricated a scapegoat.

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The aldermanic address builds on allegation of battle of absorption amid NIH advisers in 2004 and 2005, which led Director Elias A. Zerhouni to convention restrictions aftermost year on biologic aggregation consulting and added alfresco activities by NIH employees.

The new focus is on claret and added tissue samples calm by NIH scientists for analytic research, and on the NIH’s declared abridgement of an account arrangement or bright behavior to ensure that those federally endemic samples are acclimated alone for the purposes for which they were donated.

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“It’s important to bethink that anniversary of these samples originated in a being . . . that chose to accomplish a allowance so analysis could progress,” Rep. Tammy Baldwin (D-Wis.) said at yesterday’s hearing. “What is best abominable to me is the carelessness in the way in which some at NIH assume to be alleviative such a adored commodity.”

At the affection of the analysis is Sunderland’s use of analgesic aqueous calm in the aboriginal 1990s by an NIMH scientist, Susan Molchan, who after larboard the institute. When Molchan — who already filed bigotry accuse adjoin Sunderland that were bootless — accustomed to resume her analysis in a altered lab in 2004, she abstruse that abounding of her 10- to 15-year-old samples, which she hoped to retrieve, were no best in the NIMH’s freezers.

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Acting on a complaint from her, House board begin that Sunderland had beatific bags of specimens — including some of Molchan’s — to Pfizer beneath an acceding not accustomed by NIH officials. Pfizer acclimated the samples in its chase for biological markers of Alzheimer’s progression, which could accept led to a potentially advantageous test. Sunderland ultimately accustomed at atomic $285,000 in consulting fees for assignment apropos to the specimens, board said, as able-bodied as added than $300,000 for giving talks and added activities.

“In sum, the annal and interviews conducted in this analysis accession austere questions of delinquency in affiliation with, and bare blank and ascendancy over, animal tissue samples” at the NIH, the address concluded.

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NIH agent John Burklow said the bureau is “evaluating the action of actual alteration out of NIH and will be allegorical accepted rules.” Beneath the clarifications, he said, “all transfers of animal samples will crave an adapted acceding active off by a chief official.”

The NIH’s Appointment of Animal Subjects Analysis in January additionally revised its advice on the use of stored tissue samples. The new accent requires accurate tracking of all specimens and affidavit of their fate.

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